4.7

Trusted by hundreds for lasting pain relief

Get Custom Nerve Pain Relief That Actually Calms Your Neuropathy.

Stop suffering from nerve pain that burns, tingles, and numbs. Get a prescription strength formula specifically designed for your neuropathy delivered to your door for one flat price.

With Twinge Health calming the nerves is simple. Here's what you get:

Licensed pharmacist designing custom pain relief formulas

Real doctor listens to your nerve pain and prescribes your formula.

Licensed physician prescribing personalized pain relief treatment

Precision ingredients targeting your neuropathy. Not generic short lastingnumbing.

Skip pharmacy run. Your nerve pain relief cream ships free and fast with 2 day USPS Priority mail.

$79 flat price. Includes everything: Doctor consultation, custom nerve pain relief cream, and shipping.

Custom compounded nerve pain relief cream formula for neuropathy relief

Living With Neuropathy Feels Like Your Nerves Have a Mind of Their Own.

Twinge nerve pain relief cream applicator for neuropathy relief

The burning starts in your toes and creeps up your feet. The tingling in your fingertips makes it impossible to button your shirt or feel your keys. At night, when you should be resting, your nerves come alive with shooting pain that jolts you awake.

You've tried numbing creams that barely touch the surface. Swallowed nerve pills that make you dizzy without stopping the burning. Even tried "natural" remedies that promise miracles but deliver nothing but false hope and wasted money.

The reality? Generic neuropathy solutions don't understand how nerve damage actually works.

Twinge creates prescription strength formulas tailored to your exact nerve pain pattern because your diabetic neuropathy burns differently than someone else's chemotherapy induced numbness, and your path to relief should be just as unique.

Get Doctor Prescribed Nerve Pain Relief That Actually Works.

Skip the waiting rooms and endless trial and error. Get personalized, prescription strength nerve pain treatment delivered straight to your door.

Share your nerve pain story.

Tell us about your specific neuropathy symptoms like where you feel burning, numbness, or tingling, what caused it, and how it affects your daily life. Our neuropathy focused questionnaire takes just minutes. No video calls or appointment scheduling needed.

Your formula gets nerve engineered.

Custom pain relief formula crafted by medical experts

Your relief gets delivered.

Pain relief cream application and results

Step 1: Complete a Quick Nerve Pain Telehealth Consultation

Reclaim Your Nerve: Soothe the Fire, Restore the Function.

From burning sensations to numbness, each ingredient targets different nerve pathways to give you back control of your body.

Camphor

Relieves numbness and improves blood flow to damaged nerves.

Neuropathy often comes with poor circulation that makes numbness worse. Camphor boosts blood flow to affected nerves, helping restore sensation while providing soothing warmth.

Enhances blood flow to damaged nerve tissue.
Supports recovery in areas that feel numb or dead.
Provides warming relief for cold, numb extremities.

"Camphor is excellent for neuropathy patients dealing with numbness and poor circulation. It helps bring blood flow back to areas where nerves aren't getting the nutrients they need to heal properly."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Menthol

Creates cooling relief that distracts from burning nerve pain.

When your neuropathy feels like your skin is on fire, menthol provides immediate cooling relief that overrides those burning pain signals while other ingredients work deeper.

Immediate cooling effect for burning neuropathy pain.
Reduces perception of nerve pain signals to the brain.
Ideal for flare ups and breakthrough nerve pain.

"Menthol acts quickly to interrupt the pain signals nerves send to the brain. For neuropathy patients experiencing that terrible burning sensation, it offers fast relief while the other ingredients address the underlying nerve irritation."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Lidocaine

Silences the burning and stabbing nerve pain.

When neuropathy feels like fire running through your hands and feet, lidocaine steps in to quiet those overactive nerves. It's especially powerful for the burning, electric pain that keeps you awake at night.

Blocks sharp, stabbing nerve pain that feels electric.
Helps ease nighttime symptoms for better sleep.
Adjustable strength based on your nerve sensitivity.

"Lidocaine is the cornerstone for calming nerve pain in neuropathy patients. I can adjust the concentration based on how severe their nerve irritation has become. It reduces the burning sensation that patients describe as unbearable."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

NSAIDs (Diclofenac, Ibuprofen)

Targets inflammation around damaged nerves.

Inflammation around damaged nerves makes neuropathy worse and can prevent healing. Topical NSAIDs reduce this swelling without the stomach risks of oral medications.

Reduces inflammation that worsens nerve damage.
Helps prevent progression of neuropathy symptoms.
No stomach bleeding or kidney risks like oral NSAIDs.

"Topical NSAIDs are a vital part of neuropathy care because they deliver anti-inflammatory effects right to the affected nerves with minimal systemic exposure. This helps reduce the inflammation that can make nerve damage worse over time."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Amitriptyline

Calms nerves that have become hypersensitive to everything.

Chronic nerve damage makes your nerves fire pain signals even when there's no reason. Amitriptyline helps reset that hypersensitivity so your nerves only hurt when they actually should.

Addresses nerve hypersensitivity causing constant background pain.
Effective for long term neuropathy that never goes away.
Supports nerve pain relief without heavy sedation.

"Amitriptyline works by modulating the nerve pathways involved in chronic neuropathic pain. I use it especially for patients who say their feet burn even when nothing is touching them. It addresses the nerve sensitization that develops with long-term nerve damage."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Baclofen

Relaxes muscles that tense up around painful nerves.

When nerves hurt, surrounding muscles automatically tighten to protect the area. This muscle tension can make neuropathy pain worse by putting pressure on already damaged nerves. Baclofen breaks that cycle.

Releases muscle tension that compounds nerve pain.
Reduces cramping and spasms in neuropathic areas.
Helps improve circulation to nerve-damaged areas.

"Neuropathy patients often develop secondary muscle tension that makes their nerve pain worse. Baclofen helps relax those protective muscle spasms so the nerves aren't under additional pressure."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Advanced Transdermal Base

Delivers nerve relief deep through skin to damaged nerve fibers.

Neuropathy affects nerves deep under your skin where regular creams can't reach. Our pharmacist developed base carries active ingredients through multiple tissue layers to reach the actual damaged nerve fibers.

Penetrates to deep nerve fibers where neuropathy occurs.
Sustained release provides hours of nerve pain relief.
Specifically designed for peripheral nerve delivery.

"The base is everything for neuropathy treatment. You can have the best nerve pain medications in the world, but if your base can't carry them through the skin barrier to reach those damaged peripheral nerves, you're just expensive moisturizer. Our transdermal system is specifically designed for deep nerve penetration."

Dr. Javed

PharmD, RPh, Co-Founder of Twinge Health

Designed for Nerve Recovery, Not Just Surface Level Comfort.

When burning, tingling, and electric shocks disrupt your life, you need ingredients that calm overactive nerves not just mask the symptoms.

Quiet the nerves, not the mind.

Prescription-level ingredients like amitriptyline and lidocaine delivered topically—so you get powerful nerve relief without the drowsiness, brain fog, or systemic side effects of oral medications.

Stop the electric shocks.

Whether it's sudden jolts when you move or constant burning in your hands and feet, our custom formulas disrupt the nerve misfire loop at the source—not your whole nervous system.

Pain cream base penetrates directly to irritated nerve endings without affecting your balance, coordination, or mental clarity like oral nerve medications.

Restore normal sensation.

From pins and needles that won't stop to hypersensitivity that makes clothing painful, we help retrain overstimulated nerves back to normal function without numbing everything.

Safe for daily healing.

No habit forming compounds or "maximum daily dose" warnings. Designed for the long-term nerve recovery journey.

Built by experts.
Backed by real access.

Pharmacist-formulated. Doctor-approved. And you can message a real expert anytime.

They Called It a Game Changer. We Call It Personalized Nerve Pain Relief.

These reviews come from people who thought they'd tried everything for their neuropathy. Until they tried something made for their nerve pain.

Cheryl

Retired Teacher, 66

Numbness and tingling finally feel manageable

I have diabetic neuropathy in my feet. Twinge helps reduce the burning and pins-and-needles sensation.

Ron, 72

Retired Engineer

Takes the edge off my nerve pain

Shooting nerve pain in my legs used to wake me up. Twinge calms it down without pills.

Beatriz, 59

Legal Assistant

Calms the constant buzzing in my hands

I have carpal tunnel-related neuropathy. Twinge eases the nerve discomfort so I can actually type again.

Malik, 63

Delivery Driver

Helps my feet feel normal again

I have neuropathy from diabetes. I used to dread standing too long. This cream made the tingling and stinging far less intense.

Donna, 68

Artist

Better than the prescriptions I've tried

My doctor recommended a few creams, but only Twinge actually soothed my nerve pain consistently.

Henry, 61

HVAC Technician

Great for post-surgery nerve flare-ups

After back surgery, I had nerve pain down my leg. Twinge eased the burning within days.

Alina, 54

Bank Teller

I can wear shoes again comfortably

Neuropathy made even socks painful. Twinge dulled the sensitivity so I can walk without wincing.

Tomás, 58

Lab Tech

Actually helps with nerve zaps and jolts

I get these sudden nerve shocks in my calves. This cream tones them down better than anything else.

Joanne, 64

Seamstress

Nerve pain used to ruin my evenings

By dinner, my legs would burn and buzz. Twinge helped enough that I can finally relax at night.

Frequently Asked Questions About Custom Neuropathy Relief Creams.

From safety to shipping, here's everything you need to know about getting prescription-strength neuropathy relief cream delivered right to your door.

See How Twinge Compares to Your Current Pain Relief Regimen.

From appointments to disappointments, you've paid the price for pain relief that didn't deliver. Twinge is one cream that finally does.

OTC Creams

Rx Oral Pills

Twinge Cream

🛒 Access

Grab off the shelf and hope it helps.

Doctor visits, insurance hassle, and pharmacy pickup.

Quick telehealth visit with a doctor, shipped fast to your door.

⏱️ Time to Relief

Immediate if it's in stock.

Wait in line or wait for it to kick in.

Order from home and ships in two days with USPS Priority.

🧬 Personalization

Same formula for everyone.

One-size dose based on averages.

Tailored to your pain type, area, and history.

💪 Strength & Potency

Capped by over‑the‑counter limits.

Prescription strength, fixed dose.

Prescription strength, calibrated to your body needs.

😟 Side Effects

Can irritate your skin.

Risk of nausea, GI issues, liver/kidney strain, addiction.

Low systemic impact. No habit forming ingredients.

🎯 Targeting

Masks surface symptoms.

Distributes through your entire body.

Pain cream base penetrates deep into the skin to deliver powerful active ingredients right where it hurts.

⏳ Duration

Fades fast, needs reapplying often.

Wears off unevenly, leaves you chasing the next dose.

Stays active longer so you get through the day.

💰 Total Cost

$10 to $40 per tube.

$30 to $200 per month after copays and deductibles.

$79 / month

Includes custom cream, physician consult & shipping.

Questions? Chat with us

One Cream. One Price. Zero Nonsense.

From appointments to disappointments, you've paid the price for pain relief that didn't deliver. Twinge is one cream that finally does.

🛒 Access

⏱️ Time to Relief

🧬 Personalization

⚡ Strength & Potency

⚠️ Side Effects

🎯 Targeting

⏳ Duration

💰 Total Cost

OTC Creams:

$10 to $40 per tube.
Oral Pills:

$30 to $200 per month after copays and deductibles.
Twinge Custom Cream:

$79 all in — custom cream, physician consult, fast shipping.

$79/month supply. No copays. No insurance. No hidden fees.

Don't Let Another Night Be Stolen by Burning Nerve Pain

Get prescription strength neuropathy relief custom compounded for your specific nerve damage pattern. Complete consultation, personalized cream, and fast 2-day delivery, all for $79.

Order a custom nerve pain relief cream now

No insurance needed. No copays. No hidden fees. No monthly commitments. Cancel anytime.

FDA Disclaimer: Compounded medications are custom-made to meet the unique needs of each patient and are not reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety or efficacy. These formulations are prepared by licensed pharmacies in accordance with a prescription from a licensed healthcare provider. Your Twinge Health provider will determine whether a compounded topical pain cream is medically appropriate for your condition.

Emergency Substitution Disclaimer: Twinge Health services are not intended to replace emergency medical care. In case of an emergency, please call 911 or your local emergency services.

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Muscle Spasms & Strains

Sports & Overuse Injuries

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Is Twinge Right for Your Pain?

Trusted by hundreds for lasting pain relief

Get Custom Nerve Pain Relief That Actually Calms Your Neuropathy.

Stop suffering from nerve pain that burns, tingles, and numbs. Get a prescription strength formula specifically designed for your neuropathy delivered to your door for one flat price.With Twinge Health calming the nerves is simple. Here's what you get:

Real doctor listens to your nerve pain and prescribes your formula.

Precision ingredients targeting your neuropathy. Not generic short lastingnumbing.

Skip pharmacy run. Your nerve pain relief cream ships free and fast with 2 day USPS Priority mail.

Living With Neuropathy Feels Like Your Nerves Have a Mind of Their Own.

Get Doctor Prescribed Nerve Pain Relief That Actually Works.

Skip the waiting rooms and endless trial and error. Get personalized, prescription strength nerve pain treatment delivered straight to your door.

Share your nerve pain story.

Your formula gets nerve engineered.

Your relief gets delivered.

Reclaim Your Nerve: Soothe the Fire, Restore the Function.

From burning sensations to numbness, each ingredient targets different nerve pathways to give you back control of your body.

Relieves numbness and improves blood flow to damaged nerves.

Dr. Javed

Creates cooling relief that distracts from burning nerve pain.

Dr. Javed

Silences the burning and stabbing nerve pain.

Dr. Javed

Targets inflammation around damaged nerves.

Dr. Javed

Calms nerves that have become hypersensitive to everything.

Dr. Javed

Relaxes muscles that tense up around painful nerves.

Dr. Javed

Delivers nerve relief deep through skin to damaged nerve fibers.

Dr. Javed

Designed for Nerve Recovery, Not Just Surface Level Comfort.

When burning, tingling, and electric shocks disrupt your life, you need ingredients that calm overactive nerves not just mask the symptoms.

Quiet the nerves, not the mind.

Stop the electric shocks.

Pain cream base penetrates directly to irritated nerve endings without affecting your balance, coordination, or mental clarity like oral nerve medications.

Restore normal sensation.

Safe for daily healing.

Built by experts. Backed by real access.

They Called It a Game Changer. We Call It Personalized Nerve Pain Relief.

These reviews come from people who thought they'd tried everything for their neuropathy. Until they tried something made for their nerve pain.

Cheryl

Numbness and tingling finally feel manageable

Ron, 72

Takes the edge off my nerve pain

Beatriz, 59

Calms the constant buzzing in my hands

Malik, 63

Helps my feet feel normal again

Donna, 68

Better than the prescriptions I've tried

Henry, 61

Great for post-surgery nerve flare-ups

Alina, 54

I can wear shoes again comfortably

Tomás, 58

Actually helps with nerve zaps and jolts

Joanne, 64

Nerve pain used to ruin my evenings

Frequently Asked Questions About Custom Neuropathy Relief Creams.

From safety to shipping, here's everything you need to know about getting prescription-strength neuropathy relief cream delivered right to your door.

How is Twinge different from OTC neuropathy creams?

Do I need a prescription for Twinge neuropathy cream?

What types of neuropathy does Twinge help with?

Is Twinge covered by insurance?

Is it safe to use Twinge cream long term for neuropathy?

Can I use Twinge cream with my current neuropathy medications?

What if I'm allergic to certain ingredients?

Can I use Twinge cream with other neuropathy treatments?

How quickly do I see neuropathy improvements with Twinge?

What if the cream doesn't work for my neuropathy?

What if my neuropathy gets worse or spreads to new areas?

How much cream should I use and how often?

Can I use it on different areas where I have pain associated with nerve pain?

Stop suffering from nerve pain that burns, tingles, and numbs. Get a prescription strength formula specifically designed for your neuropathy delivered to your door for one flat price.

With Twinge Health calming the nerves is simple. Here's what you get:

Built by experts.
Backed by real access.